Sorkin and colleagues have derived an equivalent of the second law of thermodynamics for living systems, which establishes a relation between such a cell’s active uptake of energy and its random-looking path in terms of entropy production.
This review article discusses the concept of entropy in statistical physics and its role as both a tool for inference and a measure of time irreversibility. It highlights the developments in stochastic thermodynamics and the principle of maximum caliber, emphasizing the importance of cross-talk among researchers in disparate fields.