This study compares the incidence of acute kidney injury (AKI) following COVID-19 vaccination and infection using a large cohort study. Results show that AKI risk is significantly higher after COVID-19 infection compared to vaccination.
The study, published in npj Vaccines, compared the incidence of Acute Kidney Injury (AKI) following COVID-19 vaccination and infection in a large cohort using data from the National COVID Cohort Collaborative (N3C). The study included 6,570,021 adults, with 2,953,219 receiving vaccines and 3,616,802 contracting infection. The absolute 30-day risk of AKI was 0.66% in the vaccination group versus 4.88% in the infection group. After adjusting for confounders, COVID-19 infection was associated with a significantly higher risk of AKI than vaccination (aHR = 10.31, P < 0.001). The study validated the hypothesis that COVID-19 vaccination is associated with a lower AKI risk compared to infection. Secondary analyses across different phases of the pandemic, extended follow-up periods, and AKI measurement methods supported the primary findings.
The study, published in npj Vaccines, compared the incidence of Acute Kidney Injury (AKI) following COVID-19 vaccination and infection in a large cohort using data from the National COVID Cohort Collaborative (N3C). The study included 6,570,021 adults, with 2,953,219 receiving vaccines and 3,616,802 contracting infection. The absolute 30-day risk of AKI was 0.66% in the vaccination group versus 4.88% in the infection group. After adjusting for confounders, COVID-19 infection was associated with a significantly higher risk of AKI than vaccination (aHR = 10.31, P < 0.001). The study validated the hypothesis that COVID-19 vaccination is associated with a lower AKI risk compared to infection. Secondary analyses across different phases of the pandemic, extended follow-up periods, and AKI measurement methods supported the primary findings.
Dr. Anthony Fauci testifies at a House subcommittee hearing about the US's Covid-19 pandemic response and the origins of the virus.
Abby Haglage
