Researchers from the Chinese Academy of Sciences have identified a new organizational principle within the default mode network (DMN) that explains how it supports both internal thoughts and external perceptions. The study reveals that the DMN is composed of distinct subregions acting as either senders or receivers of information, allowing the brain to flexibly shift between memory-driven thought and sensory perception.
Key findings include:
* Identification of receiver-like subregions that support information integration during perception through stronger connectivity with heteromodal association networks.
* Identification of sender-like subregions that guide memory-based behavior via coupling with sensorimotor systems.
* Evidence that these subdivisions correspond to specific cognitive modes, such as face recognition versus memory-guided decisions.
People who consumed the highest levels of certain artificial sweeteners saw a significant decline in their ability to remember and recall words, equivalent to 1.6 years of brain aging, according to a new study.
This study explores the role of the Wnt pathway in regulating dendritic spine morphology and synaptic function. The authors found that activation of the Wnt pathway leads to the formation of new spines and enhances synaptic strength. Their findings suggest a novel mechanism by which the Wnt pathway influences synaptic plasticity and cognitive function.