klotz: neuroscience*

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  1. A new study reveals the role of the molecule KIBRA in forming long-term memories. Researchers found that KIBRA acts as a “glue,” binding with the enzyme PKMzeta to strengthen and stabilize synapses, crucial for memory retention.
  2. Recent volumetric brain reconstructions reveal high anatomic complexity. Research shows brain anatomy satisfies universal scaling laws, implying criticality in the cellular brain structure. Findings enable comparisons of structural properties across different organisms.
  3. Researchers discovered that the brain interprets negated adjectives differently than affirmative ones, exhibiting a mitigating rather than inverting effect. This finding contributes to the understanding of how the brain processes negation and other complex linguistic operations.
  4. A detailed map of the cells and synapses in a segment of a human brain sample has been created through a collaboration between Harvard and Google. The ultimate goal is to create a full map of a human brain like this, with each synapse and other structures detailed.
  5. The study identifies two common forms of variation in human brain networks: border shifts and ectopic intrusions.
    Border shifts involve changes in the borders between functional areas, while ectopic intrusions are shifts in brain organization at remote locations.
    Both forms of variants are heritable but differ in their location, network associations, activations during tasks, and prediction of behavioral phenotypes.
    2024-05-01 Tags: , , , by klotz
  6. 2024-01-04 Tags: , , by klotz
  7. New study on mice decision-making reveals that choice is not a singular moment but a reflection of the brain’s preexisting state.

    The research, using Buridan’s Assay, suggests that the mice’s brain constantly broadcasts its goal, even before options are available, with patterns of neuron activity predicting choice.

    Hunger and thirst don’t directly drive behavior; instead, they modulate the brain’s goal-setting, with an element of randomness causing switches between needs, ensuring both are met over tim
  8. consciousness relates to a dynamic process of self-sustained, coordinated brain-scale activity assisting the tuning to a constantly evolving environment, rather than in static descriptions of brain function (3–5). In that respect, neural signals combine, dissolve, reconfigure, and recombine over time, allowing perception, emotion, and cognition to happen (6).

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