Researchers from ISTA and Max Planck Institute have uncovered new details about molecular mechanisms driving memory processing at mossy fiber synapses in the hippocampus, crucial for memory formation.
The hippocampus is known to convert short-term memory into long-term memory. The study sheds light on how structural and functional changes in mossy fiber synapses may facilitate the encoding and storage of memories in the hippocampus.
The new research focuses on the mossy fiber synapse, a key connection point between neurons in the hippocampus. The scientists used a novel technique called "Flash and Freeze" combined with freeze fracture labeling to study the dynamic changes in proteins Cav2.1 calcium channels and Munc13 during signal processing. They found that upon stimulation, these proteins rearranged and moved closer together, enhancing neurotransmitter release and potentially contributing to memory formation.
The hippocampus is known to convert short-term memory into long-term memory. The study sheds light on how structural and functional changes in mossy fiber synapses may facilitate the encoding and storage of memories in the hippocampus.
The new research focuses on the mossy fiber synapse, a key connection point between neurons in the hippocampus. The scientists used a novel technique called "Flash and Freeze" combined with freeze fracture labeling to study the dynamic changes in proteins Cav2.1 calcium channels and Munc13 during signal processing. They found that upon stimulation, these proteins rearranged and moved closer together, enhancing neurotransmitter release and potentially contributing to memory formation.
A unique resource for hippocampus researchers and learners, offering tools to build and explore models of the hippocampus and its components using powerful modeling workflows.
The clearest picture yet of LUCA suggests it was a relatively complex organism living 4.2 billion years ago, a time long considered too harsh for life to flourish.
Evolutionary origin of bioluminescence in the ostracod Vargula tsujii and the integration of conserved secretory genes with novel biochemical pathways to produce light-producing signals.
* The paper explores the evolutionary origin of bioluminescence in the ostracod Vargula tsujii.
* Bioluminescence is an ecologically impactful innovation that has evolved convergently multiple times to influence predator-prey interactions and courtship signals.
* The study finds that the evolutionary novel c-luciferase gene is co-expressed with conserved genes related to toxin production and high-output protein secretion.
* This suggests that the "legacy-plus-innovation" mode of secretory evolution, previously applied to sensory modalities, also encompasses bioluminescent light as an important medium of ecological interaction and evolutionary innovation.
* The study contributes to our understanding of the evolutionary origins of bioluminescence and its significance in ecological interactions.
**Key points:**
* Bioluminescence has evolved convergently multiple times to influence predator-prey interactions and courtship signals.
* The evolutionary novel c-luciferase gene is co-expressed with conserved genes related to toxin production and high-output protein secretion.
* The "legacy-plus-innovation" mode of secretory evolution applies to bioluminescent secretions.
* The study has implications for our understanding of ecological interactions and evolutionary innovation.
* The paper explores the evolutionary origin of bioluminescence in the ostracod Vargula tsujii.
* Bioluminescence is an ecologically impactful innovation that has evolved convergently multiple times to influence predator-prey interactions and courtship signals.
* The study finds that the evolutionary novel c-luciferase gene is co-expressed with conserved genes related to toxin production and high-output protein secretion.
* This suggests that the "legacy-plus-innovation" mode of secretory evolution, previously applied to sensory modalities, also encompasses bioluminescent light as an important medium of ecological interaction and evolutionary innovation.
* The study contributes to our understanding of the evolutionary origins of bioluminescence and its significance in ecological interactions.
**Key points:**
* Bioluminescence has evolved convergently multiple times to influence predator-prey interactions and courtship signals.
* The evolutionary novel c-luciferase gene is co-expressed with conserved genes related to toxin production and high-output protein secretion.
* The "legacy-plus-innovation" mode of secretory evolution applies to bioluminescent secretions.
* The study has implications for our understanding of ecological interactions and evolutionary innovation.
Researchers have mapped the complete neural connectome of a fruit fly, detailing all 139,255 nerve cells and their connections. This advance offers insights into how the brain processes information.
This review article examines the current understanding of the origin and early evolution of eukaryotic cells, highlighting key events and players involved in this process, particularly focusing on the symbiotic relationship between an archaeal host and a bacterial endosymbiont.
This article details a data-driven exploration of owl species, using Wikipedia data to create a network visualization of owl relationships.
Explore the relationships between 2,235,473 species and discover images on a zoomable page.
- Life's evolution on Earth began with single-celled organisms and evolved into complex life forms through environmental factors and extinction events, culminating in the emergence of mammals and ultimately our own species.
- The article highlights the significance of our species, Homo sapiens, within the grand scheme of things, occurring within the last 300,000 years.
- Despite the limited time our species exists compared to the vastness of cosmic time, it encourages us to consider the potential for future life forms
- The article highlights the significance of our species, Homo sapiens, within the grand scheme of things, occurring within the last 300,000 years.
- Despite the limited time our species exists compared to the vastness of cosmic time, it encourages us to consider the potential for future life forms
