Tags: nature*

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    • TabPFN is a novel foundation model designed for small- to medium-sized tabular datasets, with up to 10,000 samples and 500 features.
    • It uses a transformer-based architecture and in-context learning (ICL) to outperform traditional gradient-boosted decision trees on these datasets.
  1. Scientists are exploring the capabilities of the DeepSeek-R1 AI model, released by a Chinese firm. This open and cost-effective model performs comparably to industry leaders in solving mathematical and scientific problems. Researchers are leveraging its accessibility to create custom models for specific disciplines, although it still struggles with some tasks.

  2. A study examining the impact of gut microbiome modulation via prebiotic supplementation on muscle function and cognitive performance in older adults, finding no significant improvement in muscle function but a beneficial effect on cognition.

  3. The study investigates how well bacterial spores maintain their structural and morphological biosignatures after exposure to harsh conditions simulating the surfaces of Enceladus and Europa. It finds that spore structure remains resilient even after exposure to radiation and temperature extremes, suggesting that methods targeting cell morphology could be valuable for future life detection missions.

  4. This study compares the incidence of acute kidney injury (AKI) following COVID-19 vaccination and infection using a large cohort study. Results show that AKI risk is significantly higher after COVID-19 infection compared to vaccination.

    The study, published in npj Vaccines, compared the incidence of Acute Kidney Injury (AKI) following COVID-19 vaccination and infection in a large cohort using data from the National COVID Cohort Collaborative (N3C). The study included 6,570,021 adults, with 2,953,219 receiving vaccines and 3,616,802 contracting infection. The absolute 30-day risk of AKI was 0.66% in the vaccination group versus 4.88% in the infection group. After adjusting for confounders, COVID-19 infection was associated with a significantly higher risk of AKI than vaccination (aHR = 10.31, P < 0.001). The study validated the hypothesis that COVID-19 vaccination is associated with a lower AKI risk compared to infection. Secondary analyses across different phases of the pandemic, extended follow-up periods, and AKI measurement methods supported the primary findings.

    2024-11-08 Tags: , , , by klotz
  5. Large language models (LLMs) are traditionally used online, but open-weights versions and smaller models are changing that, enabling researchers to run powerful AI tools locally for privacy, reproducibility, and cost-effectiveness.

    The article provides examples of researchers using local models for various tasks, including:

    • Summarizing scientific data and publications
    • Generating training data for other models
    • Transcribing and summarizing patient interviews
    • Designing novel proteins
    2024-09-17 Tags: , , by klotz
  6. 2023-08-25 Tags: , by klotz
  7. consciousness relates to a dynamic process of self-sustained, coordinated brain-scale activity assisting the tuning to a constantly evolving environment, rather than in static descriptions of brain function (3–5). In that respect, neural signals combine, dissolve, reconfigure, and recombine over time, allowing perception, emotion, and cognition to happen (6).

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